제10회 대한폐고혈압학회 학술대회
July 11-12, 2025
Coex Magok, Seoul, Korea
최정민
고려대학교 유전학과
H1-1. Unlocking the Genetic Secrets of Pulmonary Artery Hypertension: Insights from the KANK1 Discovery in the PHOENIKS Cohort
CV박진규
한림의대
H1-2. Personalized Disease Modeling of Pulmonary Hypertension Using a Multi-Organ Platform from Patient-derived iPSCs
CV진석원
광주과학기술원(GIST)
H1-3. single-cell multiomics approach to develop diagnostic tools for the early-phase PAH
CVAshfaq Ahmad
First Affiliated Hospital, Xi'an Jiaotong University, Pakistan
H2-1. ARTERIOVENOUS OXYGEN CONTENT DIFFERENCE: A DIAGNOSTIC PREDICTOR FOR PRE-SELECTING INVASIVE TREATMENT IN CONGENITAL HEART DISEASE-RELATED PULMONARY ARTERIAL HYPERTENSION
CVAbdullah M. Aldalaan
King Faisal Specialist Hospital and Research Centre, Saudi Arabia
H2-2. Preclinical Models Support the Synergistic Potential of Seralutinib and Sotatercept in Treating Pulmonary Arterial Hypertension
CVAshish Dhote
RGUHD, India
H2-3. Personalized Therapy Based on BMPR2 Mutation Status in Idiopathic PAH: A Pilot Precision Medicine Study
CVTaeil Yang
Gachon university, Gil medical center, Korea
H2-4. Mitral E Wave Deceleration Slope as A Predictor of Clinical Outcome In Pulmonary Hypertension.
CVRao Faizan
Kyung Hee University, Korea
H2-5. AI-Driven Early Detection and Risk Stratification in Pulmonary Hypertension: Leveraging Open-Source Multimodal Data
CV김성훈
자이메디
H4-1. A novel therapeutic antibody blocking inflammatory macrophage migration to treat pulmonary arterial hypertension
CV윤지열
연세의대 류마티스내과
H6-1. The hidden threat: understanding epidemiology and pathogenesis of rheumatic disease (systemic sclerosis) associated PH
CV정재현
고려의대 류마티스내과
H6-2. Advance in screening and risk stratification in rheumatic disease-associated PH
CV여지나
가천의대 류마티스내과
H6-4. Case-Based discussion: Solving real-world challenges in rheuamtic disease associated PH
CVHo Cheol Kim
Asan Medical Center , Korea
H7-1. Inhaled treprostinil in PH-ILD: new milestone therapy and future
CV
Doctor of Internal Medicine (02/2010): Seoul National University College of Medicine
Master of Internal Medicine (02/2007): Seoul National University College of Medicine
Bachelor of Medicine (02/2002): Seoul National University College of Medicine
Director of Heart Failure & Cardiac Transplantation Center (2022-): Asan Medical Center Heart Institute
Director of Cardiac Intensive Care Unit (2018-): Asan Medical Center
Professor (2024-): University of Ulsan College of Medicine
Cardiogenic shock
Acute/Chronic heart failure
Mechanical circulatory support (VA-ECMO, LVAD)
1. Trends of Left Ventricular Assist Device Implantation and Heart Transplantation in Korea. Int J Heart Fail. 2024;6:e20. (first author)
2. Left Atrial Venting versus Conventional Treatment for Left Ventricular Decompression during Venoarterial Extracorporeal Membrane Oxygenation Support: The EVOLVE-ECMO Randomised Clinical Trial. Eur J Heart Fail. 2023 Aug 24. (corresponding author)
3. Prognosis of Venoarterial Extracorporeal Membrane Oxygenation in Mixed, Cardiogenic and Septic Shock. ASAIO J. 2023 Jul 1;69(7):658-664. (corresponding author)
4. Association of cerebral blood flow with the development of cardiac death or urgent heart transplantation in patients with systolic heart failure. Eur Heart J. 2012 Feb;33(3):354-62. (first author)
5. Priming With Angiopoietin-1 Augments the Vasculogenic Potential of the Peripheral Blood Stem Cells Mobilized With Granulocyte Colony-Stimulating Factor Through a Novel Tie2/Ets-1 Pathway. Circulation. 2009;120(22):2240-50. (first author)
2006.09 ~ 2012.08 Ph.D. in Molecular Genetics
University of Maryland, College Park, MD, USA
1998.03~2004.08 B.S. in Chemistry
Yonsei University, Seoul, South Korea
2020~ Associate Professor / Department of Biomedical Sciences / Department of Biomedical Informatics / Korea University College of Medicine, Seoul, South Korea
2019~2020 Assistant Professor / Department of Biomedical Sciences / Korea University College of Medicine, Seoul, South Korea
2018~2019 Research Associate / Mentor: Richard P. Lifton, M.D., Ph.D. / Laboratory of Human Genetics and Genomics /The Rockefeller University, New York, NY, USA
2013~2018 Postdoctoral Associate / Mentor: Richard P. Lifton, M.D., Ph.D. / Department of Genetics / Yale University School of Medicine, New Haven, CT, USA
genetics, genomics, computational biology
1. Lee J, Kim Y, Lee C, Jeon SS, Seo H, Lee J, Choi J§, Kang M, Kim E, Shin K. Generation of Prostate Cancer Assembloids Modeling the Patient-specific Tumor Microenvironment. PLoS Genet. 2025 in press.
2. Kim B*, Chun H*, Lee J, Park M, Kwak Y, Kim JM, Kim SG, Ryu JK, Choi J§, Cho SJ. Predictive biomarkers for metachronous gastric cancer development after endoscopic resection of early gastric cancer. Cancer Med. 2024 Aug;13(16):e70104. doi: 10.1002/cam4.70104. PMID: 39171503; PMCID: PMC11339598.
3. Lee S*, Yoon JG*, Hong J*, Kim T, Kim N, Vandrovcova J, Yau WY, Cho J, Kim S, Kim MJ, Kim SY, Lee ST, Chu K, Lee SK, Kim HJ, Choi J§, Moon J§, Chae JH§. Prevalence and Jungmin Choi 4 Characterization of NOTCH2NLC GGC Repeat Expansions in Koreans: From a Hospital Cohort Analysis to a Population-Wide Study. Neurol Genet. 2024 May 20;10(3):e200147. doi: 10.1212/NXG.0000000000200147. PMID: 38779172; PMCID: PMC11110025.
4. Bellone S*, Jeong K*, Halle MK, Krakstad C, McNamara B, Greenman M, Mutlu L, Demirkiran C, Hartwich TMP, Yang-Hartwich Y, Zipponi M, Buza N, Hui P, Raspagliesi F, Lopez S, Paolini B, Milione M, Perrone E, Scambia G, Altwerger G, Ravaggi A, Bignotti E, Huang GS, Andikyan V, Clark M, Ratner E, Azodi M, Schwartz PE, Quick CM, Angioli R, Terranova C, Zaidi S, Nandi S, Alexandrov LB, Siegel ER, Choi J§, Schlessinger J§, Santin AD§. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2321898121. doi: 10.1073/pnas.2321898121. Epub 2024 Apr 16. PMID: 38625939; PMCID: PMC11046577
5. Miao R, Chun H, Feng X, Gomes AC, Choi J§, Pereira JP§. Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size. Nat Commun. 2022 Aug 8;13(1):4611. doi: 10.1038/s41467-022-32228-w. PMID: 35941168; PMCID: PMC9360400.
B.S., Department of Animal Science & Technology, Chung-Ang University.
Ph.D., Animal Biotechnology Major, Department of Agricultural Biotechnology, Seoul National University.
Sep/2022 – present : Assistant Professor, Department of Physiology, College of Medicine, Hallym University
Aug/2023 – present : Assistant Professor Adjunct, School of Medicine, Yale University
Dec/2019 – Aug/2022 : Associate Research Scientist, School of Medicine, Yale University
Dec/2015 – Nov/2019 : Postdoctoral Associate, School of Medicine, Yale University
Jan/2014 – Nov/2015 : Postdoctoral Fellow, Division of Animal Science, University of Missouri
1. Fabry, Cadasil and PAH disease modeling with patient-derived iPSCs to study the pathogenesis of hypertrophic cardiomyopathy, cerebrovascular disease and vascular stenosis and to develop therapeutics
2. Development of multi-organ platforms integrating heart, blood vessel, brain and lung tissues using patient-derived iPSCs and tissue engineering techniques to study cell-tissue interactions, disease pathogenesis and develop targeted therapies
1. Batty L*, Park J* and Qin L* et al., Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering, Acta Biomater. 2025;193:171-184. (*contributed equally)
2. Park J*, Riaz M*, Qin L*, Zhang W*, Batty L*, et al., Fully biologic endothelialized-tissue-engineered vascular conduits provide antithrombotic function and graft patency, Cell Stem Cell. 2025;32:1:137-143. (*contributed equally)
3. Riaz M*, Park J*, Sewanan LR* et al., Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy. Circulation. 2022;145:1238-1253. (*contributed equally)
4. Luo J*, Qin L*, Park J*, Kural MH* et al., Readily Available Tissue-Engineered Vascular Grafts Derived From Human Induced Pluripotent Stem Cells. Circulation Research. 2022;130:925-927. (*contributed equally)
5. Park J*, Anderson CW*, Sewanan LR*, Kural MH* et al., Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes. Acta Biomater. 2020;102:220-230. (*contributed equally)
Ph.D. in Bioinformatcs, Seoul National University, Seoul, Korea
M.S. in Biomedical Science(Neuroscience), Ajou University, Seoul, Korea
B.S. in Life science and Computer & information Engineering, Cheonghu University, Cheonghu, Korea
[2024-Present] Principal Researcher, Division of Cardiovascular Disease Research, Department of Chronic Disease Convergence Research, National Institute of Health, Korea
[2021-2024] Research assistant Professor, Center for KIURI Bio-Artificial Intelligence, Department of Brain Science and Neurology, Suwon , Korea
[2019-2021] Research assistant Professor, Department of Medical Informatics, Catholic University, Seoul, Korea
[2017-2019] Postdoctoral fellow, Department. of Bioconvergence analysis ,Korea Basic Science Institute Cheongju-si, Korea
Research focuses on developing AI-integrated bioinformatics approaches for precision medicine and pharmacogenomics by leveraging multi-modal omics data. The aim is to identify predictive biomarkers and model individual drug responses by integrating computational biology and data science, ultimately informing personalized therapeutic strategies.
1. JH Jhee, MY Song, BG Kim, H Shin, SY Lee. "Transformer-Based Gene Scoring Model for Extracting Representative Characteristic of Central Dogma Process to Prioritize Pathogenic Genes Applying Breast Cancer Multi-omics Data.
2. Lee, S. Y*., Wang, H., Cho, H. J., Xi, R., & Kim, T. M. The shaping of cancer genomes with the regional impact of mutation processes. Experimental & Molecular Medicine, 54(7), 1049-1060
3. Park, J*., Lee, S. Y*., Baik, S. Y*., Park, C. H., Yoon, J. H., Ryu, B. Y., & Kim, J. H. Gene-wise burden of coding variants correlates to noncoding pharmacogenetic risk variants. International journal of molecular sciences, 21(9), 3091.
4. Lee, S. Y*., Song, M. Y*., Kim, D., Park, C., Park, D. K., Kim, D. G., ... & Kim, Y. H. A Proteotranscriptomic-based computational drug-repositioning method for Alzheimer’s Disease. Frontiers in pharmacology, 10, 1653.
5. Lee, S. Y*., Hwang, H*., Kang, Y. M., Kim, H., Kim, D. G., Jeong, J. E., ... & Yoo, J. S. SAAVpedia: Identification, Functional Annotation, and Retrieval of Single Amino Acid Variants for Proteogenomic Interpretation. Journal of proteome research, 18(12), 4133-4142.
Mar, 2010 – Feb, 2017 / College of Medicine, Catholic Kwandong University, Gangneung, Korea M.D.
Mar, 2022 – Feb, 2024 / Fellowship, Cardiology, Gachon University, Gil Medical Center
Mar, 2024 – Feb, 2025 / Fellowship, Cardiology, Yonsei University, Severance Hospital
Mar, 2025 – / Clinical Assistant Professor, Cardiology, Gachon University, Gil Medical Center
General cardiology
Yang T, Jang Y, Chung WJ. Int J Heart Fail. 2024 Oct;6(4):176-178.
Won Y, Yeo J, Yang T, Chung WJ, Clin Hypertens. 2025 Jan 2:31:e5
(1977 ~ 1981) Seoul National University / BS, Pharmaceutics
(1981 ~ 1983) KAIST / MS, Biological Science
(1986 ~ 1991) Brown University / Ph.D., Biology and Medicine
(2001 ~ 2020) Seoul National University, College of Pharmacy and Graduate Program in Bioinformatics, Genetic Engineering (Professor)
(2020 ~ 2023) Yonsei University, College of Pharmacy and School of Medicine (Professor)
(2023 ~ present) Yonsei University, Institute for Convergence Research and Education in Advanced Technology, Yonsei University and School of Medicine (Professor)
(2010 ~ present) Ministry of Science and ICT, Medicinal Bioconvergence Research Center (Director)
(2021 ~ present) Zymedi Inc. (CEO)
Aminoacyl-tRNA synthetase, translation, cancer biology, therapeutic target discovery
1.Kim DG, Choi YS, Lee YN, Lim SM, Kong JW, Song JH, Roh YA, Harmalkar DS, Lee KS, Goo JI, Cho HY, Mushtaq AU, Lee JH, Park SH, Kim DY, Min BS, Lee KY, Jeon YH, Lee SK, Lee K, Kim S*. AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis. Nature Communications 13: 2572, 2022
2.Yoon I, Nam MS, Kim HK, Moon HS, Kim SM, Jang JY, Song JA, Jeong SJ, Kim SB, Cho SM, Kim YH, Lee JH, Yang WS, Yoo HC, Kim KB, Kim MS, Yang AR, Cho KK, Park HS, Hwang GS, Hwang KY, Han JM, Kim JH, Kim S*. Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1. Science 367: 205, 2020
3.Lim S, Cho HY, Kim DG, Roh YA, Sin SY, Mushtaq AU, Kim MK, Bhattarai D, Sivaraman A, Lee YJ, Lee JH, Yang WS, Kim HK, Kim MH, Lee K, Jeon YH, Kim S*. Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development. Nature Chemical Biology 16: 31, 2020
4.Thomas XN, Burrier R, Kim S*. Biocon’s target factory. Nature Biotechnology 36: 791, 2018
5.Kim JH, Lee C, Lee M, Wang H, Kim K, Park SJ, Yoon I, Jang J, Zhao H, Kim HK, Kwon NH, Jeong SJ, Yoo HC, Kim JH, Yang JS, Lee MY, Lee CW, Yun J, Oh SJ, Kang JS, Martinis SA, Hwang KY, Guo M, Han G, Han JM, Kim S*. Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction. Nature Communications 8: 732, 2017
중앙대학교 사회복지학 석사
한국외국어대학교 경영학과
한국 폐동맥고혈압 환우회 회장
세무법인원형 세무사
연세의대 1998, MD
심장초음파 인증의(KSE)
내과 레지던트, 서울아산병원
류마티스 전임의, 인하대병원
류마티스 진료교수, 세브란스병원
결체조직연관 폐질환, 폐동맥고혈압
2002 – 2008 Korea University College of Medicine, Korea; Bachelor’s degree
2013 – 2015 Korea University Graduate School, Korea; Master’s degree Internal Medicine
2016 – 2018 Korea University Graduate School, Korea; Doctor’s degree Internal Medicine
2016 – 2018 Fellow, Korea University Guro Hospital, Korea
2018 – 2019 Clinical Assistant Professor, Korea University Guro Hospital, Korea
2019 – 2020 Clinical Assistant Professor, Korea University Ansan Hospital, Korea
2020 – 2022 Assistant Professor, Korea University College of Medicine, Korea
2022 – date Associate Professor, Korea University College of Medicine, Korea
Tissue regeneration
Epidemiology
Meta-analysis
Finger-aware Artificial Neural Network for predicting arthritis in Patients with hand pain. Artif Intell Med. 2025
Intra-articular injection of stigmasterol-loaded nanoparticles reduce pain and inhibit the inflammation and joint destruction in osteoarthritis rat model: A pilot study. Drug Deliv Transl Res. 2024
Characterization of virus-mediated autoimmunity and the consequences for pathological process in patients with systemic lupus erythematosus. Clin Rheumatol. 2023
B.S., Medicine, 1999 KyungHee University Medical College, Seoul, Korea
Ph.D., 2007 KyungHee University Medical College, Seoul, Korea
Mar 2005 - Feb 2008 Instructor, Division of Rheumatology, Dept. of Internal Medicine, Catholic University Medical College, Seoul, Korea
Mar 2008 - Feb 2013 Chief, Division of Rheumatology, Dept. of Internal Medicine, Chosun University Medical College, Gwangju, Korea
Jan 2012- Dec 2012 Visiting scholarship, Clinical research center, University of California San Diego, California, USA
Mar 2013 - Present Chief, Division of Rheumatology, Dept. of Internal Medicine, Soonchunhyang University Seoul hospital, Republic of Korea
Currently, prof. Hyun-Sook Kim operates the CTD-ILD Multidisciplinary Clinic at Soonchunhyang University Seoul Hospital. Her clinical and research interests mainly focus on systemic sclerosis (SSc) and CTD-ILD, focuses on understanding the underlying mechanisms of SSc and CTD-ILD, particularly identifying novel biomarkers and potential therapeutic targets.
As of April 2025, she hold the positions of Director of Clinical Guidelines at the Korean College of Rheumatology (KCR) Association, President of the Imaging Research Group, and Advisor to the Scleroderma Research Group in KCR.
1. Full translation of “Atlas of capillaroscopy in rheumatic disease” (by Cutolo), 2017
2. Esophageal Involvement and Determinants of Perception of Esophageal Symptoms Among South Koreans With Systemic Sclerosis. Joon Seong Lee, Hyun-Sook Kim, Jung Rock Moon, Tom Ryu, Su Jin Hong, Young Sin Cho, Junseok Park, Tae Hee Lee. J Neurogastroenterol Motil. 2020;26:477-485.
3. High prevalence of salivary gland ultrasound abnormalities in systemic sclerosis. Kyung-Ann Lee, Wonho Choi, JongSun Kim, Hyun-Sook Kim. Joint Bone Spine. 2021;88:105113. doi: 10.1016/j.jbspin.2020.105113.
4. Long-term evaluation of autologous hematopoietic stem cell transplantation in a patient with progressive systemic sclerosis. Namho Kim, Jong-Sun Kim, Won-Ho Choi, Kyoung Ha Kim, Kyung-Ann Lee, Hyun-Sook Kim. Arch Rheumatol 2021;36:308-310.
5. Reliability and validity of the Korean version of the University of California-Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract instrument in patients with systemic sclerosis. Tae Hee Lee, Joon Seong Lee, Suyeon Park, Kyung-Ann Lee, Hyun-Sook Kim. Korean J Intern Med. 2021 Nov;36(6):1504-1514. doi: 10.3904/kjim.2020.190. Epub 2021 Feb 10.
6. Radiologic approach and progressive exploration of connective tissue disease-related interstitial lung disease: meeting the curiosity of rheumatologists. Hyeji Jeon, Bo Da Nam, Chong-Hyeon Yoon, Hyun-Sook Kim. J Rheum Dis 2024;31(1):3-14.
7. Effect of abatacept versus conventional synthetic disease modifying anti-rheumatic drugs on rheumatoid arthritis-associated interstitial lung disease. Kyung-Ann Lee, Bo Young Kim, Sung Soo Kim, Yun Hong Cheon, Sang-Il Lee, Sang-Hyon Kim, Jae Hyun Jung, Geun-Tae Kim, Jin-Wuk Hur, Myeung-Su Lee, Yun Sung Kim, Seung-Jae Hong, Suyeon Park, Hyun-Sook Kim. Korean J Intern Med 2024;39:855-864.
8. A pilot study of skin barrier function in patients with systemic sclerosis and primary Sjögren’s syndrome. Kyung-Ann Lee, Sooyoung Kim, Ho-Yeon Song, Moon Kyun Cho, Hyun-Sook Kim. J Rheum Dis 2024;31(4):244-252.
(2004.3-2008.2) Bechelor, Chung-Ang university (Major: Life science)
(2009.3-2013.2) M.D. College of Medicine, Gachon university
(2021.3-2024.8) on PhD course, College of Medicine, Gachon university
(2014.3-2020.2) Resident/Clinical fellow, Department of Internal Medicine, Gachon University Gil Medical Center
(2020.3-2021.2) Clinical fellow, Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital
(2021.3-2024.2) Clinical assistant professor, Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center
(2024.3- ) Assistant professor, Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center
Systemic sclerosis
Inflammatory myositis
Ankylosing spondylitis
CTD PH
Yeo J, et al. Flare prediction after tapering the dose of tumour necrosis factor inhibitors in patients with axial spondyloarthritis: A nationwide cohort study. Rheumatology (Oxford) 2025;64(3):1155-1161.
Won Y, et al. Transition from parenteral treprostinil to selexipag aiming at hemodynamic targets in pulmonary arterial hypertension. Clin Hypertens. 2025;31(1):e5.
Yeo J, et al. Quantitative interstitial lung disease scores in idiopathic inflammatory myopathies: longitudinal changes and clinical implications. Rheumatology (Oxford). 2023;62(11):3690-3699
Yeo J, et al. Utility of the breath-holding test in patients with systemic sclerosis. Rheumatology (Oxford). 2022;61(10):4113-4118.
Yeo J, et al. Angiographic characteristics of vasculopathy in patients with idiopathic inflammatory myopathies and systemic sclerosis. Sci Rep. 2022;12(1):9051.
Yeo J, et al. Pulmonary arterial hypertension due to antiphospholipid syndrome initially mimicking chronic thromboembolic pulmonary hypertension. Clin Hypertens 2022; 28(1): 10.
2004 – 2010: B.S. in Medicine, Yeungnam University, Daegu, Republic of Korea
2013 – 2015: M.S. in Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea
2018 – 2021: M.D. in Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea
2020-2024: Assistant professor, Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine
2024-2025: Visiting scholar, Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, VA, USA
2025- : Associate professor, Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine
Interstitial lung disease
Pulmonary hypertension associated with interstitial lung disease
Lung transplantation
Discrepancy between pulmonary arterial wedge pressure and left ventricular end diastolic pressure in patients with interstitial lung disease, JHLT Open. 2024 Sep 29:6:100160e, 1st author
Serial Pulmonary Hemodynamics in Patients with IPF Listed for Lung Transplant, Am J Respir Crit Care Med. 2025 Feb 10. doi: 10.1164/rccm.202411-2157OC, 2nd author
Performance of the FORD Versus Other Available Models for the Noninvasive Prediction of Pulmonary Hypertension in Patients with Interstitial Lung Disease, Lung. 2025 Jan 22;203(1):27, 1st author